Thursday, January 31, 2013

China demands an iPhone Phablet. Now!

On 30 Jan, 2013 By brian s hall

I've been consistent -- and nagging -- about an "iPhone Phablet" this year. I've said that this is a case where the market is pulling Apple. In particular, China and Asia demand that larger display.

In my piece earlier this month for Unwired View, I noted that the China factor was driving much of my thoughts on this subject.

Now, MIC Gadget chimes in with the rather plainly titled: "Apple Needs an New iPhone with Bigger Screen at a Decent Price in China".?

Apple?s revenue in China, including neighboring Hong Kong and Taiwan, totaled $7.3 billion in last quarter, up 60 percent from a year earlier. But there are signs that Apple?s vaunted cachet in the world?s most populous nation is waning. The iPhone 5 have drawn a relatively subdued response from Chinese consumers. According to Taobao.com, the biggest online marketplace in China, iPhone 5 transactions have fallen by half since it went on sale in mid-December. The iPhone is also losing out as consumers opt for bigger screens to watch Chinese soap operas while travelling, or affordable smartphones in the sub-1,000 yuan (US$160) category made by local vendors ?

?

Around half of the more than 60 million smartphones shipped in China in the third quarter last year had screens that were bigger than 4 inches, based on IDC?s latest figures.?

This year.

Wednesday, January 23, 2013

Monitoring of immune function in critically ill children with influenza reveals severe immune suppression in non-survivors

Jan. 21, 2013 ? Investigators from 15 children's medical centers, including Nationwide Children's Hospital, observed and evaluated critically ill children with influenza to evaluate the relationships between levels of systemic inflammation, immune function and likelihood to die from the illness. The study appears in the January issue of Critical Care Medicine.

The innate immune system is the cellular arm of the immune system that serves as a first-responder to new threats, and is thought to drive the inflammatory response in many forms of critical illness. Recent evidence indicates that suppression of innate immune system function can occur in critically ill patients.

This immune suppression can be quantified in the laboratory through measurement of the capacity of the patient's blood to produce a specific cytokine, tumor necrosis factor (TNF)-? , when stimulated with lipopolysaccharide (LPS), a substance which should induce a robust TNF ? response. Patients with innate immune suppression produce reduced amounts of TNF? when their blood is stimulated. In its most severe form, this condition is known as immunoparalysis. Severe reductions in TNF? production capacity have been associated with the development of secondary bacterial infections and death in critically ill adults and children.

Immune function is not routinely measured in patients with influenza, though some therapies used in this population, such as corticosteroids, can be potently immunosuppressive.

"Both pro- and anti-inflammatory therapies have been proposed as additional treatment options for influenza infection," explains lead study author Mark Hall, MD, Critical Care specialist and principal investigator in the Center for Clinical and Translational Research of The Research Institute at Nationwide Children's Hospital. "However, a lack of immune monitoring data in the pediatric population has made therapeutic decision-making difficult in children."

In this first-of-its-kind, multicenter observational study, blood samples from critically ill children with influenza were tested using highly standardized techniques to determine the capacity of the participants' innate immune system to produce TNF? when stimulated with LPS. Healthy control subjects also had their blood tested for the same properties.

Results indicated that despite high levels of circulating pro-inflammatory cytokines, critically ill children with influenza demonstrated lower TNF? production capacity compared with healthy control subjects. Further, children who died from influenza had markedly lower TNF? production capacity compared with survivors. Patients who were co-infected with influenza and the bacteria Staphylococcus aureus showed the greatest degree of immune suppression.

While the reduced capacity to produce TNF? among the critically ill children compared to healthy subjects was expected, the degree of reduction in capacity was severe enough to be highly predictive of death from the illness.

"The study demonstrates a strong relationship between mortality and reduced innate immune responsiveness in critically ill patients," said Dr. Hall, also a faculty member at The Ohio State University College of Medicine. "It also demonstrates the feasibility of large-scale immune monitoring of the kind necessary to develop and test therapies for these critically ill children. The identification of potential treatment thresholds is important because strong evidence suggests that innate immune suppression associated with critical illness may be reversible."

Advocating for additional studies, investigators suggest that patient-specific immune monitoring could aid in determining the most effective treatment for these critically ill patients. Therapies that stimulate the immune system may have a significant role in the treatment of high-risk children with severe immune suppression associated with influenza infection.

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The above story is reprinted from materials provided by Nationwide Children's Hospital.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/~3/XFmDsrTYKUI/130121122930.htm

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Speak & Deliver - A Public Speaking Blog For the Speaking Public ...

The Sound of Music

Jaws

Star Wars

Superman the Movie

Jurassic Park

Harry Potter


Could you hear the music from any or all of those movies in your mind after reading the title? Can you now? Sorry if I've put Rodgers & Hammerstein or John Williams in your head for the rest of the day. Even as I write this, I'm listening to my 'Movie Soundtrack' station on Pandora.

Music has way of embedding itself in our memories, and connecting to our life experiences. The song that played when you met your spouse, that you may have again played at your wedding. The music you use while you work out, while you study, while you write. I even used music to memorize the Periodic Table.

Music stays with us because it repeats, because it often has a simple beat or lyric refrain, and because it connects with us emotionally.

What if your speech could do the same thing? If you could embed your stories and points in your audiences brain so that it became part of the Soundtrack of their Lives?

I'm not talking specifically about music, though some top speakers intro and outro their speaking engagement with theme music.

No, YOUR speech soundtrack is your speech anchor, or series of anchors. Phrases that embody your points and your speech purpose in just a few words. Phrases that resound in your audiences heads as they leave. Phrases that, when said in a setting years later, brings back echoes of the speaker, and the ideas they passionately shared from the stage.

They are often referred to as 'Foundational Phrases', or more popularly, 'the Phrase that Pays'.

For my Toastmaster readers, the 5-7 minute format of most speeches lends itself to a single phrase, supported by 1-3 stories or examples. Ryan Avery used this method to maximum effect in his 2012 World Championship Speech, "Trust is a Must"

.

In a longer speech, it's possible to use more than one phrase - as long as they all build to the overall speech tone. Movies will often shift styles of music and create variations on a theme, while still pushing the story to one ultimate conclusion. Your phrases must do the same thing. If you have a memorable phrase for each 5-7 minute segment of your 45 minute keynote, you create a framework under your ultimate theme.

The phrases can be as few as two or three words, or as long as 8-10. They should indicate action, invoke emotion, and/or reflect results. Often, the most memorable phrases become short-hand for longer phrases, and ultimately branding for the speakers themselves.

See You at the Top! - Zig Ziglar

Eat That Frog! - Brian Tracy

It's Possible! - Les Brown


All memorable phrases - all both stand on their own, and as a piece of a larger speech or program. I'm sure you can think of a dozen more from your favorite speakers.

Whether you're putting on a keynote filled with inspirational stories, a workshop with more practical exercises and applications of your concepts, or just speaking for a few minutes to promote a singular point, finding your Soundtrack, your Phrase (or Phrases), will help you be a better speaker, and give your audience longer-lasting results. All of which will, as the saying states - help you get paid.

Like a great, pulse-pounding soundtrack, your speech needs to build emotion, and you must anchor your ideas in the minds and hearts of your audience with repetition, rhythm, and resonance to ensure they remember what you've said long after they leave your presentation. You want them using your phrases in their daily life, advising their peers and employees with the wisdom you've shared.

The ultimate moment, when you know you've successfully managed to Speak & Deliver, is when the Soundtrack of your speech becomes part of the Soundtrack of their lives.

What are your favorite phrases that have stayed with you from speakers over the years?

Source: http://speakanddeliver.blogspot.com/2013/01/make-your-speech-soundtrack-of-their.html

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the french garden shed - My French Country Home

The good thing about buying old French country homes, is that they generally come with a boat load of outbuildings .... former stables; pig sties, green houses and even bake houses.? All redundant in today's changing lifestyles, but used instead for other purposes.

These pictures are taken in the garden of a friend of mine, in the melting snow, but you can get the idea.?? A little building, dating back to 1860; an old stable perhaps, or not ... whatever.

My friend hasn't decided how to use it, so it stands empty.? Well positioned against a south facing wall,?? looking out across the width of the garden.?? At about 8' by 12' it is too small to be a guest room, not enough window light for a green house, but there must be other uses ...

?a potting shed ... a writing room .... a laundry room .....?

?

Of course he could rip off the door and make everything smart and presentable, but I'd favour finding a use that would allow him to keep the old dutch door.? I like the window shape too, with its low sill and original frame.

So tell me, what would you do to this little space to doll it up, and how would you use it if it were in your back yard?

The best ideas will be conveyed to my friend, I promise!?

Source: http://myfrenchcountryhome.blogspot.com/2013/01/the-french-garden-shed.html

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Thursday, January 10, 2013

To err is human: Fear of failure at work - Business Management Daily

Wonder what your organization?s staff is stressing over? For 28% of employees in a new Accountemps survey, it?s making a mistake at work.

The survey found that employees fear screwing up on the job more than dealing with difficult customers, conflict with managers, speaking in front of a group or fighting with co-workers.

Sure, fear of occupational failure may lead workers to take care to improve job performance and avoid mistakes. But too much worry can undermine employees? confidence and cause them to avoid even simple risks like offering new ideas. Fear of making mistakes can even hold employees back in their careers, notes Max Messmer, chairman of Accountemps and author of Managing Your Career for Dummies.

Tip: Help timid workers navigate anxiety-inducing workplace situations. Offer training on how to manage projects, set priorities, ask for help from managers, tap mentors and even make friends at work.

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Source: http://www.businessmanagementdaily.com/34131/to-err-is-human-fear-of-failure-at-work

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Is Travel Insurance Necessary? : British Expat Discussion Forum

That's a good idea about no coverage if you have to delay a flight.

And when I have been told about Alberta healthcarer covering Drs costs in the UK it is for unexpected visits but then again who knows the full story and when this actually happened.

A few pointers to travel insurance providers would be helpful as we're paying for the trip so I guess I'll be nice and pay for the insurance too.

Source: http://britishexpats.com/forum/showthread.php?t=783019

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Another Church Bombing Attempt Confirmed

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Another Church Bombing Attempt Confirmed

(Compass) - A New Year?s Eve attack against a Christian church was described as \"a deliberate attempt\" to kill or injure church members. The bomb device was concealed in a basket of chocolates and sent to a church in a town outside Dushanbe. When a church worker became suspicious, the basket was taken outside where it exploded. No one was injured. The attacked church is one of a handful of \"daughter churches\" begun in outlying towns of Tajikistan by the Grace Sonmin Church of Dushanbe. The mother congregation suffered a deadly October 1 bombing, which killed nine worshippers and wounded another 49 during a Sunday morning service. Two other bombings on December 31 damaged empty church buildings in the capital of this Central Asian state.

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Click here for details.
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Source: http://www.worldwatchmonitor.org/english/country/tajikistan/2001/newsarticle_0738.html/

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